Clinical Presentation
The clinical presentation of atopic eczema

The main clinical presentation of eczema and dry skin conditions is skin becoming scratchy, dry, cracked, and irritated.

In some cases patients will have small patches of dry skin confined to a particular area of the body, but some patients may experience inflamed skin all over the body.1

On lighter skin types, inflamed skin can turn red; on darker skin types, it can turn darker brown, purple, or grey. On darker skin, this may also be harder to see.1

The majority of new eczema cases occur in children.Although atopic eczema can affect any region of the body, in infants, eczema usually involves the face and extensor surfaces of the limbs, and may involve the trunk. A few infants may exhibit a discoid pattern. In older children, flexural involvement predominates, as in adults.2

Eczema is characterised by episodes of remission and "flares", in which symptoms are exacerbated

This can be due to a number of factors, such as stress, sleep loss or other triggers, and require an acceleration or adaptation of treatments.3

Atopic eczema is largely genetic in nature, although the exact genetic cause has not yet been identified.4 Environmental factors vary for individual patients, but generally exposure to allergens can prompt an exacerbation of eczema.4

1. NHS Conditions – Atopic Eczema. Available from: https://www.nhs.uk/conditions/atopic-eczema/. Last Accessed April 2023.
2. NICE Clinical Guideline CG57. Atopic eczema in children. December 2007.
3. Langan SM, Thomas KS & Williams HC. What is meant by a “flare” in atopic dermatitis? Arch Dermatol 2006;142:1190-1196
4. Clinical Knowledge Summaries, Eczema – atopic. http://cks.nice.org.uk/eczema-atopic#!diagnosissub. Last accessed April 2023.